One of the most rewarding “AHA” moments of bioprinting is seeing your cells proliferate within a 3D tissue. As 3D bioprinting becomes more widely adopted within the fields of tissue engineering and personalized medicine, it is important that researchers are able to monitor cell activity within a 3D structure.
Our most recent Allevi Authors tackle the method of electrochemically monitoring a tissue. Their paper, titled “Electrochemical Imaging of Cell Activity in Hydrogels Embedded in Grid-Shaped Polycaprolactone Scaffolds Using a Large-scale Integration (LSI)-based Amperometric Device”, was published in the Analytical Sciences Journal.
The researchers from Tohoku University use their Allevi 2 bioprinter to print PCL scaffolds as a support material for photocured hydrogels. They then used an amperometric device to electrochemically monitor the living cells. Through their study, they were able to determine that electrochemical imaging is a great way to monitor cell differentiation and will be useful for evaluating the viability of thicker bioprinted tissues.
Congratulations to the Tohoku University researchers on their findings!