Organ-on-a-chip technology, developed by the Wyss Institute at Harvard, has had a revolutionary impact on the field of tissue engineering by allowing the creation of models that mimic organ function and model diseases in a device that fits in the palm of your hand. We wanted to help you recreate this research in your lab with the Allevi organ-on-a-chip bioprinting protocol.
We were amazed in 2012 when we read Dr. Dongeun Huh and Dr. Donald Ingber’s paper in Science Translational Medicine that successfully created a diseased lung-on-a-chip. Their findings demonstrated the ability to identify a drug’s life-threatening toxicity that went unnoticed through traditional experimental methods, such as animal testing models. It was a milestone achievement and it inspired us to learn more about tissue engineering and its possible impact on humanity.
Since then, however, organ-on-a-chip manufacturing has mostly remained unchanged. Conventional methods give you little freedom to easily customize and create inner-chip architectures for your experimental models. We think it’s time for a change…
Today, we’re excited to offer Carbohydrate Glass from Volumetric™ Inc. and published in Nature Materials in our new 3D Organ-on-a-Chip Protocol. Carbohydrate Glass is an incredible sacrificial material that has excellent printability and makes high-resolution microchannels. This new bioink kit will provide you the ability to create custom 3D geometries within organ-on-a-chip devices and allow for design freedom to create custom in vitro organ systems that were previously not possible.
Our mission here at Allevi is to get technologies like this one into the hands of researchers who can really make a difference. We have worked closely with Dr. Jordan Miller, co-founder of Volumetric Inc, to perfect the protocol for the Allevi platform. We believe that custom organ-on-a-chip designs will be a major area of innovation for the tissue engineering and pharmaceutical community. This new organ-on-a-chip bioprinting protocol provides another unique high impact application for biofabrication to not only change the field today, but the healthcare industry tomorrow. We can’t wait to see what you will do with it.