Introducing The Allevi Tissue Layering Protocol

We’re proud to announce that we have finally achieved the ability to pattern pure collagen in an automated fashion. With our proprietary CORE™ printhead and our new Tissue Layering Protocol, you are now able to print and pattern 3 mg/mL type I collagen or 8 mg/mL type I methacrylated collagen.

Your cells are smart. They know the forces around them, what materials they are in, and can even sense the smallest details in a bioink. Have you ever wondered how pure your bioinks are? Do they contain any thickening agents that can negatively affect tissue viability and function? It’s worth a look at the datasheet the next time you consider using a new bioink in your lab.

Here at Allevi, we take great strides to source the purest bioinks that are most commonly found in our bodies. The collagens we choose, provide unparalleled results that biologists and bioengineers love. There is a challenge in doing this though; pure collagen has historically been a very difficult bioink to work with because it is difficult to pattern. Low concentrations of collagen (like the concentration found in your body) have a very low viscosity, making it hard to control the geometry of the tissue and hindering cell-directed proliferation.

We have been working in our lab for over a year trying to crack the code on low concentration collagen bioprinting. So much amazing research has already been conducted with collagen that we wanted to make it easy for you to bring that research to the next level with 3D bioprinting.

This is the first time that such low concentrations of pure collagen can be printed, patterned, and layered through 3D bioprinting. We can’t wait to see what you will do with this one!